We are deeply disappointed that television personality Denis Leary would misuse his celebrity, compromise his reputation, and exploit the real challenges of individuals with autism in making his recent extremely disrespectful and hurtful comments. His words reflect a complete ignorance of and lack of sensitivity to the true plight of families facing autism. Autism is not a joke. It is very real, especially to the families and caregivers whose lives are forever changed when their loved one receives an autism diagnosis. Autism is recognized globally as an urgent healthcare crisis. Unfortunately, in a country built on the tenets of freedom of speech, sometimes people with access to the media are able to spread harmful mistruths. We would encourage Mr. Leary to spend one day with the more than one million families affected by autism in the U.S. We believe he would quickly recognize the challenges these families face and, hopefully, develop compassion and understanding for this very real condition.