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female protective effect

Autism and the Female Protective Effect

Large study provides further evidence that more-severe genetic mutations required for a girl to develop autism than for a boy
February 27, 2014


A large new study adds evidence to the idea that something protects the developing female brain from neurodevelopmental disorders including autism. This "female protective model" proposes that more extreme genetic mutations are required for a girl to develop autism than for a boy.

The “Female Protective Effect”

February 26, 2013

A new study provides insights into why girls are much less likely than boys to develop autism

Boys are up to five times more likely to be diagnosed with autism than girls are. Researchers have proposed theories to explain why. It may be that girls are less likely to be diagnosed because their symptoms are less obvious. Or, something about a girl’s biology may protect her from developing autism.