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Autism Speaks Awards Nearly $2.7 Million in Research Grants

Autism Speaks is pleased to announce new funding for thirteen research projects that will run over the next three years, for a total investment of $2,696,703 to advance understanding and treatment of autism and its related medical conditions.

“Our Scientific Review Panel has recommended each application after thoughtfully considering critical reviews by expert panels of external reviewers, including community advocates,” says Autism Speaks Chief Science Officer Rob Ring. “The funded work in this group of projects touches upon some of the most important areas of unmet need facing the autism community today.”

Three of the research projects fall within Autism Speaks’ Early Access to Care program. Two will advance understanding of autism’s environmental risk factors. Another eight continue Autism Speaks’ long-standing focus on developing effective and accessible treatments for autism and its related medical conditions.

“These grants touch on areas of intense need including the issue of wandering, the safety of new treatments and the effective delivery of services to low-resource communities," Dr. Ring adds.

Early Access to Care

Improved screening in Latino communitiesKatharine Zuckerman and Eric Fombonne, director of the Autism Research Center at Oregon Health and Science University, will culturally adapt an ASD education and care-improvement program for use in pediatric practices serving low-income Latino communities. The researchers will test the program’s effectiveness in improving access to early screening and intervention. The study takes advantage of an existing Oregon-based program that has boosted autism screening and referrals among pediatricians

Partnering with under-resourced families. Educational psychologist Connie Kasari, of the University of California-Los Angeles, will evaluate the effectiveness of an early intervention designed to help autism therapists forge partnerships with parents in ethnically diverse, low-income communities.

Leveraging statistics to advance early access to care. Christina Bethell, of Oregon Health and Science University, will use data gathered by the school’s Child and Adolescent Health Measurement Initiative to create lay-friendly materials that will increase public and professional understanding of autism prevalence, screening and early intervention. The information will be created in various formats to meet the needs of families, providers, policy makers and advocates.

Environmental Research

A tool to assess environmental risk factors. Rebecca Schmidt, of the University of California at Davis, will test and expand the use of a method for assessing environment risk factors for autism and other neurodevelopmental disorders. This new tool may enable investigators to combine findings from multiple studies to better identify nongenetic influences that increase or decrease autism risk.

Improving autism risk communication. Michael Yudell, of Drexel University, will assess views and understanding of autism risk factors among families, researchers, clinicians, self-advocates and the wider public. The project’s findings will help Autism Speaks ensure that it is conveying new scientific information about autism risk in ways that best meet the needs of the autism community.

Treatment Innovation and Safety

Tapping non-social interests to engage toddlers. Robert Koegel, of the University of California at Santa Barbara, will evaluate an early intervention designed to increase social engagement by tapping into the intense interest in non-social stimuli often seen in toddlers with autism. By redirecting attention and interests at an early age, the intervention has potential to produce significant changes in core social behaviors and long-term social development.

Helping parents control wandering. David McAdam, of the University of Rochester, will evaluate a new parent-training program designed to reduce elopement, or wandering, in children with autism. The researchers will also develop a parent-friendly training manual.  The project is part of Autism Speaks’ large and growing investment in services that tackle the problem of wandering in families affected by autism. 

Maximizing the benefits of early intervention in urban settings. David Mandell, of the University of Pennsylvania, will assess benefits of early interventions delivered in urban settings. He will also identify personal characteristics that can help predict what programs will best serve a given child. This will lay the groundwork for studies designed to maximize the benefits of highly accessible, community-based early interventions.

Assessing age-related benefits and adverse effects of experimental medicines for Rett syndrome. Colleen Niswender, of Vanderbilt University, will use mouse models of Rett syndrome to investigate the benefits and side effects of a promising compound (an mGlu5 positive allosteric modulator) for this autism-related disorder. This work follows up on evidence that these types of compounds can benefit adults but could have adverse effects in young children affected by the syndrome. More broadly, the research will advance understanding of age-dependent safety issues and the interplay between disease progression and treatment.

Helping children with autism understand and use facial expressions. James Tanaka, of the University of Victoria in British Columbia, will develop and test a new training program (Let’s Face It! 2.0) designed to help children with ASD accurately perceive and use facial expressions in social situations.

Assessing employment skills training. Mark Klinger, of the University of North Carolina, will assess the effectiveness of the TEACCH School Transition to Employment Program (TSTEP) for adolescents and young adults with ASD. The program consists of six employment skills training modules that address ASD-related challenges to successful employment.

Parent intervention for reducing problem behaviors in preschoolers. Benjamin Handen, of the University of Pittsburgh, will assess the effectiveness of Parent-Child Interaction Therapy for reducing problem behaviors in preschoolers with ASD. The investigators will also adapt a training manual previously written for parents of grade-schoolers.

Improving treatment of psychiatric crises in individuals with ASD. Roma Vasa, of Baltimore’s Hugo Moser Research Institute at Kennedy Krieger, will investigate the prevalence and risk factors for psychiatric crises in individuals with ASD. She will assess how caregivers and psychiatrists respond to these crises and develop a psychiatric-crisis assessment tool. This will lay the groundwork for developing better methods for the prevention and treatment of psychiatric crises in the autism community.

You can explore all the research Autism Speaks is funding using this website’s grant search

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