In the November issue of the American Journal of Human Genetics, NAAR-funded researchers Drs. James Millonig, Emanuel DiCicco-Bloom and Linda Brzustowicz at
In addition to the human genetic studies, Dr. DiCicco-Bloom, a neurobiologist at UMDNJ who also serves on the NAAR Scientific Advisory Board, demonstrated a mechanism by which alterations in this gene may lead to altered neuronal function. The experiments described in this article demonstrate a neurobiological link between neuronal development and genetic susceptibility, crossing both the basic and clinical sciences through collaborative research. NAAR continues to fund the exploration of the involvement of this gene in ASD by continuing to fund research projects led by both Drs. Millonig and Dr. George Wagner at
This research has led to greater funding for autism susceptibility genes from the NIH, however, Dr. Millonig remarks: “These studies would not have been possible without NAAR support.” For more information on this study click here.