"Grant Type","Year","Title","Description","Investigator/Fellow","Institution","Award Type","Location","Findings","Publications"
"","2011","Defining the Underlying Biology of Gastrointestinal Dysfunction in Autism","Autism Spectrum Disorders (ASD) are behaviorally defined by impairments in communication, social interactions, and repetitive stereotypic behaviors. Many children...","Ashwood, Paul","University of California, Davis","Suzanne and Bob Wright Trailblazer","Davis, CA","",""
"","2009","Evaluation of the immune and physiologic response in children with autism following immune challenge.","The overall goal of this proposal is to address immune function in children with autism, including the response to vaccine challenge, and how that relates to behavior...","Van de Water, Judy","University of California, Davis","Basic & Clinical","Davis, CA","",""
"","2010","The role of neuroinflammation in ASD-related behaviors, hyper-excitability and epilepsy","The biological basis of autism spectrum disorder (ASD) is poorly understood, but research strongly suggests that, aside from genetic predisposition, the body's immune...","Barth, Daniel","University of Colorado, Boulder","Pilot","Boulder, CO","",""
"","2008","Interactions of environment and molecular pathways on brain overgrowth in autism: Maternal inflammation and the PI3/AKT pathway","It has been recently reported that some individuals with autism show premature brain overgrowth early in development. This may be the result of more brain cells,...","Le Belle, Janel","University of California, Los Angeles","Environmental","Los Angeles, CA","",""
"","2008","Influence of maternal cytokines during pregnancy on effector and regulatory T helper cells as etiological factors in autism","Despite the specific genes or environmental exposures which may contribute to ASD, one theme that emerges from clinical and experimental studies is inflammation and...","Ponzio, Nicholas","University of Medicine and Dentistry","Environmental","Newark, NJ","",""
"","2008","Influence of Oxidative Stress on Transcription and Alternative Splicing of Methionine Synthase in Autism","Many cases of autism are thought to develop due to environmental exposures acting on genetically vulnerable individuals. Potential environmental exposures encompass...","Muratore, Christina","Northeastern University","Predoctoral Fellowships","Boston, MA","",""
"","2007","Influence of maternal cytokines on activation of the innate immune system as a factor in the development of autism","Clinical and basic studies indicate a role for the immune system in autism. One idea is that a maternal immune response during pregnancy can influence embryonic...","Mandal, Mili","University of Medicine and Dentistry","Predoctoral Fellowships","Newark, NJ","",""
"","2007","Augmentation of CA CADDRE Studies","Since 2001, the California Center for Autism and Developmental Disabilities Research and Epidemiology (CA CADDRE) has been one of the largest, most extensive datasets...","Croen, Lisa","Kaiser Permanente","Basic & Clinical","Oakland, CA","",""
"","2006","Is autoimmunity involved in pathogenesis of autism?","Many neuropathological studies in autism have reported a reduction in numbers of cells in the brain in areas which control motor coordination and cognitive...","Kawikova, Ivana","Yale University","Pilot","New Haven, CT","",""
"","2011","Early life environmental exposures and autism in an existing Swedish birth cohort","Large autism spectrum disorders (ASD) studies utilizing biobanks such as the National Children's Study are planned or underway but the financial cost of following...","Lee, Brian","Drexel University","Basic & Clinical","Philadelphia, PA","",""
"","2012","Molecular analysis of gene-environment interactions in the intestines of children with autism","Gastrointestinal (GI) disturbances are commonly reported in children with autism, complicate clinical management and may contribute to behavioral impairment. Evidence...","Williams, Brent","Columbia University","Basic & Clinical","New York, NY","",""
"","2013","Targeting RORgt activity to prevent the development of ASD-related phenotypes","The exact cause of autism spectrum disorders (ASD) is still unknown, but accumulating evidence from human and mouse model studies suggest that abnormal function of...","Wong, Helen","New York University","Predoctoral Fellowships","New York, NY","",""